Computing is a necessary component of high-dimensional data analysis. I have written programs for analyzing genetic linkage data, and am also developing software for quantifying gene expression in large sets of Affymetrix GeneChips.
Linkage
An extension to the score test method is in development:
D-test
Mixture model-based test for genetic linkage under heterogeneity (Fortran program)
ST-rels
Score test for genetic linkage based on identity by descent data on relative pairs (C program)
MIST-rels
Multiple imputation score test for genetic linkage with missing data on relative pairs (C program in development)
Microarrays
I am also currently working to implement Multiple Partition Resampling and other methods as an R package, in development for the
BioConductor Project.
affyRX
Resampling and subsampling methods for multichip quantification of gene expression for high density short oligonucleotide arrays (Affymetrix GeneChips) in large data sets
(R/BioConductor package in development)
